Palladium-catalyzed carbocyclization of 1,6-enynes leading to six-membered rings or oxidized five-membered trifluoroacetates.
نویسندگان
چکیده
We describe palladium-catalyzed carbocyclization of 1,6-enynes leading to six-membered rings by water-originated hydride addition. Mechanistic features of this anomalous carbocyclization and isolation of a chiral five-membered C-Pd intermediate as an oxidized form of trifluoroacetate are also reported.
منابع مشابه
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عنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 101 16 شماره
صفحات -
تاریخ انتشار 2004